Fumarate hydratase-IN-1( —— )

Catalog No. M32930 CAS No. 1644060-37-6

Fumarate hydratase-IN-1 is a cell-permeable fumarate hydratase inhibitor with antiproliferative activity and can be used to study cellular activity.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Fumarate hydratase-IN-1
Note

Research use only, not for human use.
Brief Description

Fumarate hydratase-IN-1 is a cell-permeable fumarate hydratase inhibitor with antiproliferative activity and can be used to study cellular activity.
Description

Fumarate hydratase-IN-1 (compound 2) is a cell-permeable fumarate hydratase inhibitor. Fumarate hydratase-IN-1 has antiproliferative activity against several cancer cell lines with a mean IC50 of 2.2 μM.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Mitochondrial Metabolism
Research Area

——
Indication

——

Chemical Information

CAS Number

1644060-37-6
Formula Weight

446.54
Molecular Formula

C27H30N2O4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (111.97 mM; Ultrasonic )
SMILES

CCOC(=O)[C@@]12CCCC=C1N(Cc1ccc(cc1)-c1ccccc1)C(=O)[C@H]2CC(=O)NC
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Takeuchi T et al. Identification of Fumarate Hydratase Inhibitors with Nutrient-Dependent Cytotoxicity. J Am Chem Soc, 2015 Jan 21, 137(2): 564-567.?

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